Cancer's link to a lack of cholesterol

This paper was published in Nature Reviews. Molecular Cell Biology 2004 Jan;5(1):45-54

Study title and authors:
From polyploidy to aneuploidy, genome instability and cancer.
Storchova Z, Pellman D.
Department of Pediatric Oncology of The Dana-Farber Cancer Institute, Children's Hospital and Harvard Medical School, Room M621A, 44 Binney Street Boston, Massachusetts 02115, USA.

This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/14708009

Storchova notes that a growing amount of evidence indicates that polyploid cells arise during a variety of pathological conditions.

Aneuploidy is an abnormal number of chromosomes. Chromosome abnormalities occur in 1 of 160 live births, the most common that infants can survive with is an extra chromosome 21, which is found in Down syndrome.                  

Genetic instability in polyploid cells might lead to aneuploidy (which is associated with tumors) and thereby contribute to the development of cancer.

Polyploid cells may arise by a lack of cholesterol. See here.

AMAZON USA Timeless Secrets of Health and Rejuvenation
AMAZON USA Timeless Secrets of Health and Rejuvenation